For example, 1000 cal of eating Twinkies will result in the difference between eating 1000 cal of beef liver.

Or, consuming 1000 cal of white sugar is different than consuming 1000 cal of beef heart.

Also, the reason why all these “0 cal“ sweeteners are so pernicious is that they still make you fat.

Coke zero makes you fat, stevia makes you fat, etc.