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July 30, 2025
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Mitochondrial hormesis (mitohormesis)
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Research shows that there’s real science behind your statement! When researchers massaged one leg of athletes after exhausting cycling, the tissue biopsies revealed higher expression of the “master regulator” of mitochondrial biogenesis, PGC‑1α, along with lower nuclear NF‑κB activity and reduced inflammatory cytokines (TNF‑α and IL‑6) compared with the untreated leg . The massage therapy effectively dampened inflammation and promoted the growth of new mitochondria in skeletal muscle . This is the cellular underpinning of what’s often called a “deep tissue massage”; by mechanically loading muscle fibres it appears to trigger signalling pathways that encourage your cells to build more powerhouses and recover faster.
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